Research Domain Criteria (RDoC)
The goal of this new manual, as with all previous editions, is to provide a common language for describing psychopathology. While DSM has been described as a “Bible” for the field, it is, at best, a dictionary, creating a set of labels and defining each. The strength of each of the editions of DSM has been “reliability” – each edition has ensured that clinicians use the same terms in the same ways. The weakness is its lack of validity. Unlike our definitions of ischemic heart disease, lymphom...
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DSM to be replaced with a matrix of quantifiable measures.
Causality as a Conceptual Tool
Causality itself is an evolved conceptual tool that simplifies, schematizes, and focuses our representation of situations. This cognitive machinery guides us to think in terms of the cause—of an outcome’s having a single cause. Yet for enlarged understanding, it is more accurate to represent outcomes as caused by an intersection, or nexus, of factors (including the absence of precluding conditions). In War and Peace, Tolstoy asks, “When an apple ripens and falls, why does it fall? Because of ...
1 John Tooby on how causation is a way we simplify the world to more easily understand it, but it can also over-simplify.
I am my connectome
http://www.goodreads.com/book/show/11346470-connectomeWe know that each of us is unique, but science has struggled to pinpoint where, precisely, our uniqueness resides. Is it in our genes? The structure of our brains? Our genome may determine our eye color and even aspects of our personality. But our friendships, failures, and passions also shape who we are. The question is: how? Sebastian Seung, a dynamic professor at MIT, is on a quest to discover the biological basis of identity. He believes it lies in the pattern of connections between the brain’s neurons, which change slowly over time as we learn and grow. The connectome, as it’s called, is where our genetic inheritance intersects with our life experience. It’s where nature meets nurture. Seung introduces us to the dedicated researchers who are mapping the brain’s connections, neuron by neuron, synapse by synapse. It is a monumental undertaking—the scientific equivalent of climbing Mount Everest—but if they succeed, it could reveal the basis of personality, intelligence, memory, and perhaps even mental disorders. Many scientists speculate that people with anorexia, autism, and schizophrenia are "wired differently," but nobody knows for sure. The brain’s wiring has never been clearly seen. In sparklingly clear prose, Seung reveals the amazing technological advances that will soon help us map connectomes. He also examines the evidence that these maps will someday allow humans to "upload" their minds into computers, achieving a kind of immortality. Connectome is a mind-bending adventure story, told with great passion and authority. It presents a daring scientific and technological vision for at last understanding what makes us who we are. Welcome to the future of neuroscience
The Problem with the DSM
Currently, diagnosis in mental disorders is based on clinical observation and patients’ phenomenological symptom reports. This system, implemented with the innovative Diagnostic and Statistical Manual-III (DSM-III) in 1980 and refined in the current DSM-IV-TR (Text Revision), has served well to improve diagnostic reliability in both clinical practice and research. The diagnostic categories represented in the DSM-IV and the International Classification of Diseases-10 (ICD-10, containing virtua...By clustering symptoms into categories of mental illness, we are treating symptoms, not underlying causes.
Social Norms and Psychological Disorders
Before 1980, this would have seemed a strange question. Social anxiety disorder did not officially exist until it appeared in that year’s Diagnostic and Statistical Manual, the DSM-III, the psychiatrist’s bible of mental disorders, under the name “social phobia.” It was not widely known until the 1990s, when pharmaceutical companies received F.D.A. approval to treat social anxiety with S.S.R.I.’s and poured tens of millions of dollars into advertising its existence. The current version of ...Shyness becomes "Social Anxiety Disorder" because we live in a society that values outgoing people over people who are introspective.
